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Biology HSC Science (General) 12th Standard Board Exam Maharashtra State Board Syllabus 2025-26

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Maharashtra State Board 12th Standard Board Exam Biology Syllabus - Free PDF Download

Maharashtra State Board Syllabus 2025-26 12th Standard Board Exam: The Maharashtra State Board 12th Standard Board Exam Biology Syllabus for the examination year 2025-26 has been released by the MSBSHSE, Maharashtra State Board. The board will hold the final examination at the end of the year following the annual assessment scheme, which has led to the release of the syllabus. The 2025-26 Maharashtra State Board 12th Standard Board Exam Biology Board Exam will entirely be based on the most recent syllabus. Therefore, students must thoroughly understand the new Maharashtra State Board syllabus to prepare for their annual exam properly.

The detailed Maharashtra State Board 12th Standard Board Exam Biology Syllabus for 2025-26 is below.

Academic year:

Maharashtra State Board 12th Standard Board Exam Biology Revised Syllabus

Maharashtra State Board 12th Standard Board Exam Biology and their Unit wise marks distribution

Maharashtra State Board 12th Standard Board Exam Biology Course Structure 2025-26 With Marking Scheme

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Syllabus

1: Reproduction in Lower and Higher Plants [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus

2: Reproduction in Lower and Higher Animals [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus

3: Inheritance and Variation [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus

4: Molecular Basis of Inheritance [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus

5: Origin and Evolution of Life [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus

6: Plant Water Relation [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus
  • Plant Water Relation  
  • Properties of Water  
    • Introduction
    • Activity 1
    • Activity 2
    • Activity 3
  • Water Available to Roots for Absorption  
  • Absorption and Conduction of Water and Minerals  
    • Imbibition  
    • Concept of Osmosis  
      • Meaning
      • Forms
      • Experiments
      • Duration of Osmosis
    • Passive Transport  
  • Water Potential (ψ)  
    • Water Potential (ψ)
    • Factors affecting water absorption
  • Path of Water Across the Root  
    • Pathway of water across the root
    • Two ways of Pathway of water
    1. Apoplast pathway
    2. Symplast pathway: Vacuolar and Transmembrane
  • Translocation of Water (Ascent of Sap)  
    1. Root Pressure Theory (Vital Theory)
    2. Capillarity theory (physical force theory)
    3. Cohesion-tension theory (Transpiration pull theory)
    4. Adhesion
  • Transport of Mineral Ions  
  • Transport of Food  
    • Path of translocation
    1. Vertical translocation 
    2. Lateral translocation
    • Mechanism of sugar transport through phloem
  • Transpiration  
  • Types of Transpiration  
    • Types of Transpiration
    1. Stomatal Transpiration
    2. Cuticular transpiration
    3. Lenticular transpiration
  • Structure of Stomatal Apparatus  
    • Opening and Closing of Stoma
  • Significance of Transpiration  

7: Plant Growth and Mineral Nutrition [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus
  • Plant Growth  
    • Plant Growth
    • Aspect of growth:
    1. Quantitative aspect of growth
    2. Qualitative aspect of growth
    • Meristems:
    1. Apical meristem
    2. Intercalary meristem
    3. Lateral meristem
  • Phases of Plant Growth  
    • Phases of Plant Growth
    1. Phase of cell division/ formation (Meristematic Phase)
    2. Phase of cell enlargement/ elongation (Elongation Phase)
    3. Phase of Cell maturation/ differentiation (Maturation Phase)
  • Conditions Necessary for Plant Growth  
  • Plant Growth Rate  
    • Growth Rates
      1) Arithmetic growth
      2) Geometric growth
  • Plant Growth Curve  
    • Growth curve:
      a) Lag Phase
      b) Log Phase
      c) Stationary Phase
  • Differentiation, De-differentiation, Re- Differentiation  
  • Plant Development  
  • Plant Plasticity  
  • Plant Hormones  
    • Plant Hormones
    • Types of Plant Hormones
  • Types of Plant Hormones: Auxins  
    • Auxins
    • Physiological effects and applications of auxin
  • Types of Plant Hormones: Gibberellins  
    • Gibberellins
    • Physiological effects and application of Gibberellins
  • Types of Plant Hormones: Cytokinins  
    • Cytokinin
    • Physiological effects and applications of cytokinin
  • Types of Plant Hormones: Ethylene  
    • Ethylene
    • Physiological effects and application of ethylene
  • Types of Plant Hormones: Abscisic Acid (ABA)  
    • Abscisic Acid
    • Physiological effects and application of ABA
  • Photoperiodism  
    • Photoperiodism
    1. Short Day Plants (SDP)
    2. Long Day Plants (LDP)
    3. Day Neutral Plants (DNP)
    • Phytochrome
  • Vernalization (Yarovization)  
    • Vernalization
    • Advantages of vernalization
  • Plant Mineral Nutrition  
    • Sources of minerals
    • Classification of minerals on the basis of their quality requirement:
    1. Essential minerals 
    2. Non-essential minerals 
    • Classification of minerals on the Basis of their quantity requirement:
    1. Microelement minerals
    2. Macroelement minerals
    • Symptoms of Mineral deficiency in plants
    • Toxicity of Micronutrients
    • Minerals salt absorption: Passive Absorption and Donnan equilibrium
  • Biogeochemical Cycles (Nutrient Cycles)  

8: Respiration and Circulation [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus

9: Control and Co-ordination [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus
  • Control and Co-ordination  
  • Nervous System in Hydra  
  • Nervous System in Planaria (Flatworm)  
  • Neural Tissue  
    • Neuroglial Cells (Or Glial Cells)  
      • Neuroglial cells
      • Neuroglia Functions 
      • Types of  Glial cells and Their Functions
      1. Microglia
      2. Macroglia
      3. Astrocytes
      4. Oligodendrocytes
      5. Ependymal Cells
      6. Radial Glial Cells
      7. Schwann Cells
      8. Satellite Cells
      9. Enteric Glia Cells
  • Neuron (Or Nerve Cell) and Its Types  
    • Neuron
    • Types of neurons
    1. Unipolar neurons
    2. Bipolar neurons
    3. Multipolar neurons
    4. Sensory or afferent neurons
    5. Motor or efferent neurons
    6. Association (connecting) neurons
    • Nerve
    • Types of Nerve
    1. Sensory nerves
    2. Motor nerves
    3. Mixed nerves
    • Difference between Neuron and Nerve
  • Human Nervous System  
    • Introduction
    • Components of Nervous System
    • Neuron
    • Need of Nervous System
  • Central Nervous System (CNS)  
    • Central Nervous System
    • Different regions of Brain and its functions
  • The Human Brain - Forebrain  

    Forebrain: 

    1. Olfactory lobes
    2. Cerebrum
    3. Diencephalon

     

  • The Spinal Cord  
    • Spinal Cord 
    • T. S. of spinal cord
    • Functions of the spinal cord
  • Peripheral Nervous System (PNS)  
    • Peripheral Nervous System
    • Types of PNS
  • Sensory Receptors  
    • Sensory Receptor
    • Classification of receptors
    1. Exteroceptors: Receive external stimuli
    2. Interoceptors : Receive stimuli coming from within the body

  • Human Eye  
    • Structure and Components
    • Photoreceptors and Eye Muscles
  • Human Ear  
    • Structure of Human Ear
    • Function of Human Ear
  • Disorders of Nervous System  
    • Psychological disorders
    • Parkinson's disease
    • Alzheimer’s disease
  • Chemical Coordination  

    Chemical Coordination

    1. Autocrine 
    2. Paracrine 
    3. Endocrine 
    4. Pheromone 
  • Human Endocrine System  

    Human Endocrine System

    • Properties of Hormones 
    • Mechanism of hormone action 
  • Human Endocrine Glands  
    • The Hypothalamus  
      • The Hypothalamus: Neurosecretory cells
      • Hormones produced by hypothalamus are of two types:
        (i) Releasing hormones
        (ii) Inhibiting hormones
    • Pituitary Gland or Hypophysis Gland  
      • Pituitary gland
      • Division of pituitary gland
        (i) Adenohypophysis (anterior pituitary): Pars distalis, pars tuberalis
        (ii) Neurohypophysis (posterior pituitary): Pars nervosa, infundibulum, MSH (Melanocyte Stimulating Hormone)
      • Hormones of adenohypophysis/ hormones of pars distalis:
        (i) Growth Hormone (GH)
        (ii) Thyroid-stimulating hormone (TSH)
        (iii) Adrenocorticotropic hormone (ACTH)
        (iv) Prolactin
        (v) Follicle-stimulating hormone (FSH)
        (vi) Luteinizing hormone (LH)
      • Hormones of neurohypophysis
    • The Pineal Gland  
      • Pineal gland
      • Function of melatonin
    • Thyroid Gland  
      • Thyroid gland: Isthmus, Follicles and stromal tissues, tetraiodothyronine or thyroxine (T4), triiodothyronine (T3), thyrocalcitonin (TCT), Iodine
      • Functions of thyroid hormones
      • Disorders related to thyroid gland
      1. Hyperthyroidism
      2. Hypothyroidism
    • Parathyroid Gland  
      • Parathyroid gland
      • Functions of parathyroid hormone
    • Thymus Gland  
      • Thymus gland
      • Function of thymosins
    • Adrenal Gland (Suprarenal Gland)  

      Adrenal Gland

      • Hormones and functions of adrenal gland
        (i) Adrenal cortex: Zona reticularis, Zona Fasciculata, Zona reticularis
      • Disorders related to Adrenal cortex: Hyposecretion, Hyper secretion
        (ii) Adrenal medulla: Adrenaline, Nor-adrenaline, Catecholamines, emergency hormones or hormones of fight or flight
    • Pancreas (Islets of Langerhans)  
      • Pancreas (Islets of Langerhans): α-cells and β-cells
        (i) Insulin
        (ii) Glucagon
      • Other hormone secreting cells of islets of Langerhans
        (i) Delta or D cells
        (ii) F cells
      • Disorders related to pancreas

              -Diabetes mellitus (Hyperglycemia)

    • Reproductive Glands (Gonads)  

      Gonads

      • Ovaries
      • Testes
    • Diffuse Endocrine Glands  

      Diffuse endocrine glands

      • Placenta
      • Gastrointestinal tract
      • Kidney
      • Heart
      • Hormone therapy/ HT
  • Synapse - Properties of nerve fibres  
    • Synapse
    • Properties of nerve fibres
  • Synapse - Types of synapse  

    Types of synapses

    1. Electrical synapse
    2. Chemical synapse
  • Transmission of nerve impulse  
  • Generation of nerve impulse  

    Generation of nerve impulse

    1. Depolarization
    2. Re-polarization
  • Reflex Action  
    • Reflex Action
    • Types of Reflex actions
  • Autonomic Nervous System (ANS)  
    • Autonomic Nervous System
    • Reflex Action

10: Human Health and Diseases [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus
  • Defence System in Our Body: Immune System  
    • Immune System
    • Cells of Immune System
    1. Lymphocytes
      - Mechanism of response of T-lymphocytes to antigens
      - Mechanism of action of B-lymphocytes to antigens
    2. Antigen Presenting cells

     

  • Vaccination and Immunization  
    • Vaccination
    • Immunization
  • Structure of Antibody  
    • Antibody
    • Immunoglobulins
    • Structure of Antibody
    • Formation of antigen-antibody complex
    • Antigen on Blood Cells
    • ABO Blood Groups
    • Rh factor
  • Disease  
    • Introduction
    • Identification of disease
  • Common Diseases in Human Beings  
    • Bacterial Diseases  
      • Bacterial diseases in human beings
      • Typhoid ( Enteric fever)
      • Pneumonia
      • Shigellosis (Bacillary dysentery)
      • Bubonic plague (Black death)
      • Diphtheria
      • Cholera
      • Tetanus (Lock jaw)
      • Tuberculosis
      • Syphilis
      • Whooping cough (Pertussis)
      • Dysentery
      • Plague
    • Fungal Diseases  
      • Fungal diseases
      • Ringworm (Dermatophytosis)
      • Athlete’s foot
  • Vector Borne Diseases  
    • Vector
    • Vector Borne Diseases: Mosquitoes, Cockroaches and Rats
    1. Malaria
    2. Elephantiasis (filariasis)
    3. Yellow fever
    4. Dengue
    • Control of mosquitoes:
    1. Spraying
    2. Elimination of breeding places
    3. Spraying on stagnant water
    4. Biological control
  • Cancer  
    • Introduction of Cancer
    • Differences between normal cell and cancer cell
    • Causes of cancer
    • Cancer detection and diagnosis
    • Treatment of cancer
    • Scope of Immunology
  • Concept of Adolescence  
    • Introduction
    • Meaning
    • Stages of Adolescence
    • Development of Sexual and Secondary Sexual Characters
    • Physical Changes during Adolescence
    • Emotional and Social Changes
    • Adolescence as a Phase
  • Addiction  
  • Drug Abuse  
    • Drugs, Tobacco, and Alcohol Use- An Invitation to Death
    • Effects of Drug and Alcohol Abuse
    • Prevention and Control of Drug Abuse
10.02 Excretion and Osmoregulation [Revision]
  • Modes of Excretion: Ammonotelism, Ureotelism, and Uricotelism  
    • Modes of Excretion
    1. Ammonotelism
    2. Ureotelism 
    3. Uricotelism 
    • Nephridiopores
    • Types of nephridia
    1. Protonephridia
    2. Metanephridia
  • Human Excretory System  
    • Introduction
    • Human Excretory System Organs
    • Excretion in Humans
    • Mechanism of Excretion in Humans
    • Dialysis
  • Function of the Kidney - “Production of Urine”  
    • Ultrafiltration
    • Reabsorption
    • Tubular secretion (Renal Secretion)
    • Distal convoluted tubule (DCT)
    • Collecting duct
  • Regulation of Kidney Function  
    • Osmoregulation
    • Regulation of Kidney Function
    1. Renin-Angiotensin,
    2. Atrial Natriuretic Factor (ANF)
    3. ADH and Diabetes Inspidus
  • Common Disorders of the Urinary System  
    • Kidney stones
    • Uremia
    • Nephritis
    • Renal Failure
    • Diabetes
    • Urinary tract infection
    • Haemodialysis
    • Peritoneal dialysis 
    • Kidney transplant
    • Renal Calculi
    • Glomerulonephritis

11: Enhancement of Food Production [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus
11.01 Human Reproduction [Revision]

12: Biotechnology [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus
  • Biotechnology  
    • Introduction to Biotechnology
    • Benefits of Biotechnology
  • Principles of Biotechnology  
    • Tools and techniques for gene cloning/ rDNA technology  

      Tools and techniques for gene cloning/rDNA technology

      1. Different instruments (devices) 

      • Polymerase chain reaction (PCR)
      • Mechanism of PCR

      2. Biological tools

      1. Enzymes
      2. Cloning vectors
      3. Competent hosts
  • Methodology for rDNA Technology  
    1. Isolation of DNA (gene) from the donor organism
    2. Insertion of a desired foreign gene into a cloning vector (vehicle DNA)
    3. Transfer of rDNA into the suitable competent host or cloning organism
    4. Selection of the transformed host cell
    5.  Multiplication of transformed host cell
    6.  Expression of the gene to obtain the desired product
  • Commercial Applications of Biotechnology  
    • Transgenic Plants  

      Transgenic Plants

      • Advantages of GM food-plants 
      1. Insect pest resistance
      2. Improved nutritional qualities (biofortification)
      3. Modification in Post-harvest characteristics
      4. Plants as factories
      5. Transgenic plants producing edible vaccines
    • Transgenic animals  
  • Bioethics  

    Bioethics

  • Effects of Biotechnology on the Environment  
    • Herbicide Use and Resistance
    • Effects on Untargeted Species
  • Biopiracy  
  • Effects of Biotechnology on Human Health  

    Effects of Biotechnology on Human Health

    • Allergies
    • Long-Term Effects
    • New Proteins
    • Food Additives

13: Organisms and Populations [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus

14: Ecosystems and Energy Flow [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus

15: Biodiversity, Conservation and Environmental Issues [Revision]

Maharashtra State Board 12th Standard Board Exam Biology Syllabus

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